The PhIP-Seq platform
Develop and maintain the production PhIP-Seq pipeline and codespace on the JHU Rockfish HPC system, including phipmake2, an R library for post-alignment summarisation across multi-library screens.
When a run finishes, the reads and the metadata that says which library they belong to go through alignment, library splitting, beads-only background modelling, hit calling, annotation, and taxon-level aggregation. Which partition each step runs on is a judgment call rather than a fixed recipe.
From sequencing run to shared results